Pathophysiology of antiphospholipid antibodies.
نویسندگان
چکیده
The presence of antiphospholipid antibodies in plasma is a risk factor for thromboembolic complications. In vitro, however, the same antibodies can prolong dotting times in coagulation assays, a classic marker for a bleeding tendency. For years this contradiction has puzzled many scientists. Recently new insights into the interaction between antiphospholipid antibodies and their main target, the protein beta-2-glycoprotein I, have opened new avenues for the understanding of the pathology of this syndrome.
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عنوان ژورنال:
- The Netherlands journal of medicine
دوره 62 8 شماره
صفحات -
تاریخ انتشار 2004